SENS Research Foundation Releases 2013 Research Report
The SENS Research Foundation coordinates and conducts research into the baseline technologies needed for human rejuvenation. We age because we become damaged: cells and the structures between cells...
View ArticleAnother Way to Improve Memory in Old Mice
In recent years researchers have demonstrated a number of ways to improve memory in old laboratory mice. Here is another: If you forget where you put your car keys and you can’t seem to remember things...
View ArticleA Short Overview of 3-D Printing in Tissue Engineering
Technologies derived from rapid prototyping and 3-D printing will likely play an important role in the future of tissue engineering, just as they are coming to do in many fields: The field of tissue...
View ArticleLife Without Ageing: Aubrey de Grey and Tom Kirkwood to Debate Longevity...
The British Science Festival will be held in Newcastle a few weeks from now. One of the events has Aubrey de Grey of the SENS Research Foundation, advocate and coordinator for rejuvenation research,...
View ArticleCalorie Restriction as a Means to Augment Cancer Therapies
Long term calorie restriction lowers the risk of cancer in addition to extending life in laboratory animals. Here researchers show that short term calorie restriction appears to augment the...
View ArticleDamaging the Biology of Mice to Make them Age More Rapidly Often Tells Us...
Aging is damage: it is the accumulation of broken and obstructed protein machinery and nanoscale structures inside and around our cells. Living beings come with many varied repair systems, so the...
View ArticleA Look Back at Some of the Roots of Modern Thought on Radical Life Extension
The modern movements of transhumanism and support for longevity science have deep roots: you can find early expressions of the ideas of human enhancement and overcoming natural limits on our biology in...
View ArticleThe Next Few Years of Research Into Alzheimer’s Disease
A conservative view of what lies ahead for Alzheimer’s disease (AD) research sees incremental progress resulting from new and better investigative biotechnologies: In the recently published work “The...
View ArticleA Two-Part Report on Global Futures 2045
The 2045 Initiative is a fairly young but comparatively well-backed effort to generate more support for and technological progress towards non-biological means of human life extension: artificial...
View ArticleChildren of Long-Lived Parents Have Better Immune Systems
The immune system declines greatly with aging, and poor immune response is an important component of age-related frailty: old people become vulnerable to infections that the young can shrug off with...
View ArticleDecreased mTOR Expression Provides 20% Mean Life Span Extension in Mice
Mammalian (or mechanistic, depending on who you ask) target of rapamycin (mTOR) is the most likely candidate for the next round of billion-dollar research funding devoted to the search for drugs that...
View ArticleA Collagen Patch to Spur Heart Tissue Repair
Building patches for damaged hearts is a popular implementation in tissue engineering at the moment: it’s an achievable stepping stone on the way to more complex goals, such as the creation of entire...
View ArticleStatin Use Correlates With Higher Telomerase Activity
There has been interest in extending increasing telomerase expression as a means to slow aging for some years. The available tools other than gene therapy are sparse on the ground, however. Telomerase...
View ArticleMeasuring the Impact of Cytomegalovirus in Younger People
Cytomegalovirus (CMV) is one of the less immediately harmful members of the family of herpesviruses. It is very prevalent: most people have it in their system by the time they are old, but probably...
View ArticleComprehensive Therapy Regimen Shown to Reverse Symptoms of Early Alzheimer’s...
In a groundbreaking new clinical trial, three patients suffering from mild to moderate degenerative memory loss experienced a reversal of their misfortune as a result of a new medical...
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Seven Traits Associated with Good Health and Longevity
When we talk about what it takes to live a long life, we have a tendency to get hung up on the physical parameters associated with wellness, whether it be diet, exercise, or the myriad of other...
View ArticleThe Current State of Knowledge of Genetics and Longevity
The interaction between genes, metabolism, and natural variations in longevity is an enormously complex space. This complexity is why efforts to slow aging by altering metabolism are doomed to be a...
View ArticleSigns of Progress: Insurers Talk of Radical Life Extension
I had somehow missed this event from earlier in the year, a provocative (by mainstream standards) ad campaign mounted by a portion of the insurance industry: “The First Person To Live To 150 Is Alive...
View ArticleThe Cost of Living Longer, Even in Good Health
There are many comparatively simple genetic alterations that enable animals of various different laboratory species to live between 10% to 60% longer. These are changes to the operation of metabolism:...
View ArticleTargeting Redox Biology to Reverse Mitochondrial Dysfunction
Mitochondria are the power plants of the cell, generating chemical fuel stores that can be used to power cellular processes. They are important in aging, and this has a lot to do with the generation of...
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